Olmesartan–Hydrochlorothiazide is prescribed to treat high blood pressure (hypertension). This combination medication is composed of two drugs namely Olmesartan and Hydrochlorothiazide. Olmesartan relaxes blood vessels thereby allowing easy blood flow and Hydrochlorothiazide helps eliminate extra water and salt from your body. Olmesartan–Hydrochlorothiazide lowers high blood pressure thereby preventing kidney problems, strokes, and heart attacks. This medicine may also be used to treat other conditions as determined by your doctor.

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What does Olmesartan–Hydrochlorothiazide treat?

Olmesartan–Hydrochlorothiazide is a combination medicine that treats blood pressure. It consists of Olmesartan which relaxes blood vessels easing blood flow and Hydrochlorothiazide which eliminates extra water and salt. This falls under the class of angiotensin receptor blocker (ARB). Your physician may use this to treat other ailments based on their discretion.

Possible Side Effects

Olmesartan–Hydrochlorothiazide might have some side effects but it’s not possible to anticipate them. It does not have any major side effects and the minor ones that may occur are temporary. In rare cases, there might be major side effects and immediate medical attention must be sought.

Some of the side effects could be heartburn, diarrhea, joint pain, dizziness, stomach pain, headache and upper respiratory tract infections. Serious side effects are rare but may include chest pain, shortness of breath, confusion, fever, rapid weight gain, and yellowing of the skin or eyes. This is not the complete list though.

In case, there is a change in intensity of side effects or if any new side effects develop, make sure you consult your doctor.

Dosage Instructions

Follow the Olmesartan–Hydrochlorothiazide dosage prescribed by your physician. The dosage could vary based on individual patient requirements. Always follow your physician’s instructions or go by the directions on the prescription drug label. Make sure you have it with a whole glass of water. You can take it with or without food. This medication is not recommended during pregnancy or breastfeeding. Make sure you do not drive, use machinery, or perform any activity that needs alertness. Avoid prolonged exposure to the sun.


Missed a dose?

Take it immediately once you remember. In case, this time falls close to the next dosage, skip it and get back to the prescribed schedule. Never take a double dose unless your physician specifically directs you to do so.


Don’t waste any time and seek immediate medical attention. Overdosing on this drug may have you encounter symptoms such as fast or slow heartbeat, fainting, and severe dizziness.

Drug Interactions

Drug interactions must be considered before starting to take any kind of drug. Drug interactions might happen either when Olmesartan–Hydrochlorothiazide is taken along with another drug or with particular foods. To prevent any kind of negative interaction, make sure you inform your doctor of any drugs you are taking including non-prescription medication, OTCs, health supplements like vitamins, minerals, herbal medicine, drinks with caffeine and alcohol, illegal drugs, smoking habits and so on which may increase the effect of Olmesartan–Hydrochlorothiazide.

It may interact with:


  • Furosemide
  • Glipizide
  • Ibuprofen
  • Lithium


It may also interact with potassium-sparing diuretics, non-steroidal anti-inflammatory drugs, corticosteroids, cough-and-cold products, barbiturates and diabetes medicines. This is not the complete list though.

Appraise your doctor of any medical conditions that you are suffering from and your family history of medical ailments. It’s important that you do not stop or start taking any medicine without the consent of your physician.

What to ask your doctor before you start on Olmesartan–Hydrochlorothiazide


  • Can I take Olmesartan–Hydrochlorothiazide along with other drugs? 
  • Are there certain foods, beverages and products to be avoided while on Olmesartan–Hydrochlorothiazide? 
  • What is the dosage of Olmesartan–Hydrochlorothiazide to be consumed? 
  • How should I use Olmesartan–Hydrochlorothiazide? 
  • How will Olmesartan–Hydrochlorothiazide work on my body? 
  • How can the drug interactions and side effects of Olmesartan–Hydrochlorothiazide be minimized or completely avoided?



The health and medical information that we have provided are meant to supplement and not substitute the advice of your physician, pharmacists or other health care professionals. This does not suggest that usage of Olmesartan–Hydrochlorothiazide is safe, appropriate or effective for you. Always ensure that you take this or any other drug only after consulting your physician.